Figure: dCMP catabolic process (Mouse)¶
This diagram illustrates the dCMP catabolic process in mouse (Mus musculus) as described in the GO-CAM model. The pathway occurs in the cytosol (GO:0005829) and shows the sequential enzymatic reactions involved in breaking down dCMP.
The pathway proceeds through six main steps: 1. dCMP is converted to deoxycytidine by 5'-nucleotidases Nt5c (MGI:1354954) and Nt5c3 (MGI:1927186) 2. Deoxycytidine is deaminated to deoxyuridine by cytidine deaminase Cda (MGI:1919519) 3. Deoxyuridine is processed by uridine phosphorylases Upp1 (MGI:1097668) and Upp2 (MGI:1923904) 4. The resulting product is converted by dihydropyrimidine dehydrogenase Dpyd (MGI:2139667) 5. N-carbamoyl-β-alanine is then processed by dihydropyrimidinase Dpys (MGI:1928679) 6. Finally, β-alanine is further metabolized by β-ureidopropionase Upb1 (MGI:2143535)
All proteins shown are encoded by mouse genes with their respective MGI identifiers indicated in the GO-CAM model.
Feedback from AI on figure:
{"feedback":"This diagram effectively illustrates the dCMP catabolic process in mouse within the cytosol compartment. The sequential enzymatic reactions are clearly depicted with a logical flow and numbered steps, making it easy to follow the pathway from start to finish. \n\nThe design uses appropriate scientific visualization conventions with:\n- Clear representation of metabolites as circles with readable labels\n- Enzymes shown as rectangular boxes with their gene symbols\n- Directional arrows indicating reaction flow\n- Numbered reaction steps for easy reference\n- Informative legend explaining the diagram elements\n- Functional annotations for each enzyme\n\nThe improved font sizes enhance readability, and the inclusion of GO IDs and metabolite identifiers provides scientific precision suitable for a journal publication. The clean, minimalist style aligns well with figures typically found in high-impact journals like Cell or Nature.","necessary_changes":null,"optional_changes":null}