Figure: AMP salvage 2b, from adenosine (Mouse)¶
This diagram illustrates the AMP salvage pathway in mouse cells (GO:0044209), showing how adenosine is recycled to form AMP through five enzymatic steps:
- Ada (Adenosine deaminase, MGI:87916) converts adenosine to inosine
- Pnp (Purine-nucleoside phosphorylase, MGI:97365) converts inosine to hypoxanthine
- Hprt1 (Hypoxanthine phosphoribosyltransferase, MGI:96217) converts hypoxanthine to IMP
- Adss1 (Adenylosuccinate synthase, MGI:87947) converts IMP to adenylosuccinate
- Adsl (Adenylosuccinate lyase, MGI:103202) converts adenylosuccinate to AMP
The pathway is represented in a style suitable for publication in journals such as Cell or Nature, with enzymes shown as pink rectangles and metabolites as circles. Green circles represent intermediate metabolites, while the blue circle represents AMP, the final product of the salvage pathway.
Feedback from AI on figure:
{"feedback":"The diagram effectively illustrates the AMP salvage pathway from adenosine in mouse cells as described in the GO-CAM model. The representation follows a clear, logical flow that accurately shows the step-by-step enzymatic reactions. Each enzyme (Ada, Pnp, Hprt1, Adss1, and Adsl) is properly labeled and positioned alongside its respective reaction. The metabolites are distinctly visualized using appropriately sized circles with consistent styling, and the final product (AMP) is highlighted with a different color to emphasize its role as the endpoint of the pathway.\n\nThe layout adheres to scientific journal illustration standards, with professional color coding, clear labeling, and appropriate use of space. The inclusion of the GO term reference adds scientific credibility. The diagram successfully balances technical accuracy with visual clarity, making it suitable for publication in journals like Cell or Nature.","necessary_changes":null,"optional_changes":null}