Figure: Glucuronate catabolic process to xylulose 5-phosphate (Mouse)¶
The diagram depicts the D-glucuronate catabolic process to D-xylulose 5-phosphate (GO:0019640) in mouse cytosol. The pathway consists of five sequential enzyme-catalyzed reactions:
- Akr1a1 (L-glucuronate reductase, GO:0047939) converts L-glucuronate to L-gulonate
- Cryl1 (L-gulonate 3-dehydrogenase, GO:0050104) converts L-gulonate to 3-dehydro-L-gulonate
- Dcxr (L-xylulose reductase, GO:0050038) converts 3-dehydro-L-gulonate to L-xylulose
- Sord (D-xylulose reductase, GO:0046526) converts L-xylulose to D-xylulose
- Xylb (D-xylulokinase, GO:0004856) converts D-xylulose to D-xylulose 5-phosphate (CHEBI:57737)
All reactions occur in the cytosol (GO:0005829) and are part of the same biological process. Each enzyme is represented by a colored oval while metabolites are shown as green rectangles. The final product (D-xylulose 5-phosphate) is highlighted in pink.
Feedback from AI on figure:
{"feedback":"The diagram presents the glucuronate catabolic process to xylulose 5-phosphate in mouse cells with excellent clarity and scientific accuracy. The pathway is depicted with proper enzyme names and their functions, showing the sequential conversion from L-glucuronate to the final product D-xylulose 5-phosphate. Each enzyme is visually distinguished using different colored ovals, while metabolites are consistently represented with green rectangles, creating an intuitive visual hierarchy. The arrows clearly indicate reaction directionality, and the inclusion of enzyme function labels adds scientific context without overwhelming the diagram. The cellular localization in the cytosol is appropriately indicated, and the legend provides clear guidance on interpreting the diagram elements. The overall layout follows conventions typical of high-quality journal figures in publications like Cell or Nature, making it suitable for scientific publication.","necessary_changes":null,"optional_changes":null}