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Figure: Dermatan sulfate catabolic process (Mouse)

id: gomodel:62900b6400002879

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This figure depicts the dermatan sulfate catabolic process in mouse lysosomes (GO:0030209).

The diagram shows five key enzymes involved in the sequential degradation of dermatan sulfate: - ARSB (N-acetylgalactosamine-6-sulfatase, MGI:88075) - IDS (iduronate-2-sulfatase, MGI:96417) - HEXA (beta-N-acetylhexosaminidase, MGI:96073) - HEXB (beta-N-acetylhexosaminidase, MGI:96074) - IDUA (L-iduronidase, MGI:96418)

All enzymatic activities occur within the lysosomal compartment (GO:0005764). The arrows represent causal relationships between different enzymatic activities, with color-coding to distinguish between sequential steps in the pathway. The substrate (dermatan sulfate) is broken down through multiple enzymatic steps, ultimately resulting in catabolized products.

Feedback from AI on figure:

{"feedback":"The SVG drawing effectively illustrates the dermatan sulfate catabolic process in mouse lysosomes as described in the GO-CAM model. The figure has been created in a style appropriate for a scientific journal, with clear labeling, logical flow, and professional aesthetics.\n\nThe drawing successfully depicts the five key enzymes (ARSB, IDS, HEXA, HEXB, and IDUA) and their relationships within the lysosomal compartment. The use of high-contrast color-coded arrows makes the causal relationships between enzymatic activities immediately clear. Text is highly readable with appropriate font sizes and weights. The legend provides a concise explanation of the pathway components and relationships.\n\nThe diagram balances scientific accuracy with visual clarity, making it suitable for publication in high-impact journals like Cell or Nature.","necessary_changes":null,"optional_changes":null}