Figure: Zearalenone biosynthesis (Gibberella zeae)¶
The diagram illustrates the zearalenone biosynthesis pathway in Gibberella zeae. The pathway begins with acetyl-CoA and malonyl-CoA as substrates, which are processed by three enzymes: ZEA2 (polyketide synthase), ZEA1 (catalytic enzyme), and ZEB1 (oxidoreductase), ultimately producing zearalenone. These enzymatic activities are positively regulated by ZEB2, a transcriptional activator that influences all three enzymes in the pathway. Dashed boxes represent intermediate products (not explicitly mentioned in the source data) shown for clarity of the biochemical process. Solid arrows indicate catalytic conversion, while dashed orange arrows represent regulatory activation.
Feedback from AI on figure:
{"feedback":"The final diagram effectively illustrates the zearalenone biosynthesis pathway in Gibberella zeae with scientific accuracy and visual clarity. The pathway components are well-organized, with appropriate color-coding and shapes distinguishing between substrates, enzymes, intermediates, and the final product. The addition of inferred intermediate molecules (clearly marked as not in the original source) enhances understanding of the biochemical process without misrepresenting the data. The regulatory role of ZEB2 as a transcriptional activator is clearly depicted with dashed orange arrows connecting to all three enzymes. The legend provides comprehensive explanations of all visual elements, making the diagram suitable for publication in a high-impact scientific journal.","necessary_changes":null,"optional_changes":null}