Figure: B cell receptor signaling pathway 1 (Mouse)¶
This diagram illustrates the B cell receptor signaling pathway in mouse based on the GO-CAM model. The pathway begins with the B cell receptor complex (CD79a and CD79b) at the cell membrane, which initiates intracellular signaling. The signal propagates through Syk (protein tyrosine kinase), which activates mSHC1 (protein-macromolecule adaptor). mSHC1 then activates Grb2 (guanyl-nucleotide exchange factor adaptor), which in turn activates both Sos1 and Sos2 (guanyl-nucleotide exchange factors). Each protein is depicted with its molecular function, and the arrows indicate the direction of signal transduction through the pathway.
Feedback from AI on figure:
{"feedback":"The diagram effectively illustrates the B cell receptor signaling pathway, with a clear representation of the key components and their interactions. The use of distinct shapes and colors for different proteins enhances readability, while the labeled arrows clearly show the direction of signal flow. The addition of a comprehensive legend explains abbreviations and provides context for the molecular functions of each component.","necessary_changes":null,"optional_changes":"For future iterations, different arrow styles or colors could be used to represent various types of interactions or regulatory relationships within the pathway."}