Figure: Pyruvate catabolic process 1 (Mouse)¶
This diagram illustrates the pyruvate catabolic process in mouse cells (GO:0042867) as represented in the GO-CAM model. The pathway shows how pyruvate, produced during glycolysis, is converted to lactate in the cytosol and then transported out of the cell.
Key components: - Pkm (MGI:97591): Pyruvate kinase involved in glycolytic process - Lactate dehydrogenases: Ldha (MGI:96759), Ldhb (MGI:96763), and Ldhc (MGI:96764) convert pyruvate to lactate in the cytosol - Lactate transporters: Slc16a1 (MGI:106013) and Slc16a3 (MGI:1933438) transport lactate across the plasma membrane
The diagram represents cellular compartments (cytosol, plasma membrane, extracellular region), proteins (green rectangles), metabolites (blue ovals), biological processes (orange rectangles), and reaction pathways (arrows).
Feedback from AI on figure:
{"feedback":"This diagram effectively conveys the pyruvate catabolic process pathway in mouse cells with scientific accuracy and visual clarity. The layout presents a logical flow from glycolysis to extracellular lactate transport, with all key components properly labeled with both common names and GO/MGI identifiers. The cellular compartments are clearly delineated, and the use of different shapes and colors helps distinguish between proteins, metabolites, and processes. The curved arrows effectively show the reaction pathways without crowding, making the relationships between components easy to follow. Font sizes have been increased for better readability, and the included legend provides clear explanation of the visual elements used in the diagram.","necessary_changes":null,"optional_changes":null}