Figure: Positive regulation of glycolytic process 1 (Mouse)¶
This figure depicts the positive regulation of glycolytic process in mouse, showing key interactions between four proteins in the cytosol. Ppp2ca (protein phosphatase) and Gpi1 (glucose-6-phosphate isomerase) both positively regulate Pfkfb1 (6-phosphofructo-2-kinase), which produces fructose-2,6-bisphosphate. This metabolite acts as an allosteric activator of Pfkl (6-phosphofructokinase), which catalyzes a key step in the glycolytic process through fructose-6-phosphate. The entire pathway contributes to the positive regulation of glycolysis, as described in GO:0045821.
Feedback from AI on figure:
{"feedback":"The diagram effectively illustrates the positive regulation of the glycolytic process in mouse, showing the key interactions between Ppp2ca, Gpi1, Pfkfb1, and Pfkl within the cytosol. The use of color-coding helps distinguish between different proteins and metabolites, while the clearly labeled arrows with mechanism descriptions enhance understanding of the regulatory relationships. I added semi-transparent background boxes behind the arrow text to improve contrast and readability. The legend provides valuable reference information including GO terms for each component. Overall, this figure would be suitable for publication in high-impact journals like Cell or Nature, as it presents complex molecular interactions in a clear, accessible format.","necessary_changes":null,"optional_changes":null}