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Figure: Glycogen biosynthetic process (Dmel)

id: gomodel:65d7e4ac00002167

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This diagram illustrates the glycogen biosynthetic process in Drosophila melanogaster (fruit fly) as described in the GO-CAM model. The pathway occurs in the cytosol and involves five key enzymes:

  1. Pgm1 (Phosphoglucomutase, FBgn0003076) - Converts α-D-glucose 6-phosphate to α-D-glucose 1-phosphate
  2. UGP (UTP:glucose-1-phosphate uridylyltransferase, FBgn0035978) - Converts α-D-glucose 1-phosphate to UDP-α-D-glucose
  3. Gyg (Glycogenin, FBgn0265191) - Initiates glycogen synthesis using UDP-α-D-glucose as substrate
  4. Glys (Glycogen synthase, FBgn0266064) - Elongates the glycogen chain through addition of glucose units
  5. Agbe (1,4-alpha-glucan branching enzyme, FBgn0053138) - Creates branch points in the glycogen structure

The diagram shows the sequential nature of the process, with causal relationships between enzymes. All reactions occur in the cytosol compartment, consistent with the GO-CAM annotation (GO:0005829), and collectively contribute to the glycogen biosynthetic process (GO:0005978).

Feedback from AI on figure:

{"feedback":"This pathway diagram effectively captures the glycogen biosynthesis process in Drosophila melanogaster as specified in the GO-CAM model. The diagram is clear, well-structured, and aesthetically pleasing, making it suitable for publication in journals like Cell or Nature. The addition of transformation labels, enzyme action indicators on reaction arrows, and causal relationship annotations significantly enhances understanding of the pathway's sequential nature.","necessary_changes":null,"optional_changes":null}