Figure: Positive regulation of glycogen catabolic process 2 (Mouse)¶
This figure illustrates the positive regulation of glycogen catabolic process in mouse (GO-CAM model: gomodel:65f3ae5c00002270). The pathway occurs in the cytosol and begins with Phkg1 (phosphorylase kinase gamma 1) positively regulating Pygb (brain glycogen phosphorylase). Pygb acts on glycogen and initiates three downstream pathways: 1) Agl (amylo-alpha-1,6-glucosidase, 4-alpha-glucanotransferase) with its dual enzymatic activities; 2) Pgm1 (phosphoglucomutase-1); and 3) Pgm2 (phosphoglucomutase-2). Both Pgm1 and Pgm2 catalyze the conversion to alpha-D-glucose 6-phosphate, the end product of this glycogen breakdown pathway. Different enzyme types are color-coded as shown in the legend.
Feedback from AI on figure:
{"feedback":"The drawing effectively illustrates the positive regulation of the glycogen catabolic process pathway in mice. The design is clear and professional, suitable for publication in scientific journals like Cell or Nature. The key elements of the pathway are accurately represented, with well-defined relationships between the different enzymes and metabolites.","necessary_changes":null,"optional_changes":"Additional detailing of the chemistry involved in each enzymatic step could further enhance the scientific value of the illustration, but might also make it more complex."}