Figure: nitrogen cycle metabolic process (GO:0071941)¶
This figure illustrates the nitrogen cycle metabolic process in Schizosaccharomyces pombe, focusing on the urea cycle and related pathways.
The diagram represents two major interconnected processes: 1) The urea cycle (orange, GO:0000050): This circular pathway begins with carbamoyl phosphate synthesis by Arg4 and Arg5, followed by citrulline formation (Arg3), argininosuccinate synthesis (Arg12), and arginine production (Arg7, Arg41). The cycle completes with arginase activity (Aru1, Car1) converting arginine to urea.
2) Urea metabolism (green, GO:0019627): Multiple pathways feed into this process. The urease complex (Ure2, Ure4, Ure6, Ure7) breaks down urea into ammonia (NH₄⁺). Additional pathways process nitrogen-containing compounds: Uro1 acts on uric acid, Dal2 processes allantoin, and multiple agmatinases (Agm1, Agm2, Agm3) convert agmatine to urea.
Fumarate is produced as a byproduct during argininosuccinate breakdown. The interconnections between these pathways demonstrate the complex nitrogen recycling mechanisms in S. pombe.
Feedback from AI on figure:
{"feedback":"The drawing effectively illustrates the nitrogen cycle metabolic process in S. pombe with clear organization and visual hierarchy. The color coding distinctly separates the urea cycle (orange) from urea metabolism pathways (green), making the different processes immediately distinguishable. The standardized text sizes and improved spacing prevent label overlap, enhancing readability throughout the diagram.\n\nThe thicker directional arrows clearly guide viewers through the metabolic processes, and the addition of a key pathway interactions section provides helpful context about the biological significance of the pathways. The legend is comprehensive and explains all visual elements used in the diagram.\n\nThe detailed representation of enzyme activities with their corresponding gene products accurately reflects the GO-CAM model data. Overall, this is an excellent scientific illustration that would be appropriate for publication in journals like Cell or Nature.","necessary_changes":null,"optional_changes":null}