Figure: tryptophan biosynthetic process (GO:0000162)¶
This figure illustrates the tryptophan biosynthetic pathway (GO:0000162) in Schizosaccharomyces pombe. The pathway occurs within the cytosol (GO:0005829) and consists of five enzymatic steps involving four different gene products.
The pathway begins with chorismate (CHEBI:29748) and L-glutamine (CHEBI:18050) as substrates for anthranilate synthase (trp3/SPCC1442.09, GO:0004049). The reaction proceeds through anthranilate phosphoribosyltransferase (trp4/SPBC16G5.08, GO:0004048), followed by phosphoribosylanthranilate isomerase (trp1/SPBC1539.09c, GO:0004640). The same gene product (trp1) also catalyzes the subsequent step as indole-3-glycerol-phosphate lyase (GO:0033984). The final step is catalyzed by tryptophan synthase (trp2/SPAC19A8.15, GO:0004834), producing tryptophan (CHEBI:27897) and glyceraldehyde 3-phosphate (CHEBI:17138) as the end products.
Each enzyme in the pathway is color-coded for visual clarity as indicated in the legend. Arrows represent the directional flow of metabolites through the pathway.
Feedback from AI on figure:
{"feedback":"The illustration effectively communicates the tryptophan biosynthetic pathway in S. pombe cells. The color-coded enzymatic steps create clear visual distinction between the different reactions, while maintaining a coherent overall design. The pathway flow is logically arranged and easy to follow from inputs to outputs. The addition of a legend explaining the color scheme enhances understanding for independent viewing. Font sizes are appropriate throughout, ensuring all text is readable. The cellular context (cytosol) is clearly indicated, providing important biological context. Overall, this illustration meets the professional standards expected for publication in high-tier scientific journals like Cell or Nature.","necessary_changes":null,"optional_changes":null}