Figure: Protein lipoylation 1 (Mouse)¶
This diagram illustrates the protein lipoylation pathway in mouse mitochondria as described in the GO-CAM model. The pathway shows four key enzymes (Lipt2, Lias, Lipt1, and Dlat) operating sequentially within the mitochondrion. Each enzyme is represented by a colored box containing its gene symbol and ID, with its molecular function shown in a matching colored box below. Solid arrows between enzymes indicate causal "enables" relationships, while dashed arrows show "part of" relationships to biological processes. Lipt2, Lias, and Lipt1 participate in protein lipoylation (GO:0009249), while Dlat participates in the pyruvate catabolic process (GO:0042867). All activities occur within the mitochondrion (GO:0005739), represented by the oval background.
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{"feedback":"This pathway diagram effectively illustrates the protein lipoylation process in mouse mitochondria with excellent clarity and scientific accuracy. The sequential pathway with the four key enzymes (Lipt2, Lias, Lipt1, and Dlat) is well-represented with distinct color coding that helps differentiate between the different molecular functions. The causal relationships are clearly indicated by solid arrows labeled 'enables', while dashed arrows appropriately show the 'part of' relationships to biological processes. The mitochondrial context is properly indicated by the oval background representing the mitochondrion, with subtle inner membrane detailing that adds biological context without overwhelming the diagram. The text is highly readable with appropriately sized fonts and bold labels for emphasis on key elements. The addition of a comprehensive legend enhances understanding of the color scheme and arrow types used in the diagram.","necessary_changes":null,"optional_changes":null}