Figure: TCA cycle, aerobic respiration - imported from: Saccharomyces Genome Database

id: gomodel:YeastPathways_TCA-EUK-PWY

Color codes indicate different enzyme classes (oxidoreductases in green, transferases in pink, hydratases in purple, ligases in red, and carboxylases in blue). Metabolites are shown as colored circles. Cellular compartments are indicated by dashed borders (cytosol in blue, mitochondrion in light red, and mitochondrial inner membrane in darker red). Arrows show reaction directionality, with cofactors (NAD+/NADH, CoA) and products (CO2) labeled.

Feedback from AI on figure:

{"feedback":"This scientific illustration faithfully represents the TCA cycle in yeast (Saccharomyces cerevisiae) based on the GO-CAM data. The drawing effectively visualizes the cycle's major elements:\n\n1. Clarity and organization: The diagram presents a clean, publication-ready visualization that would be suitable for journals like Cell or Nature. The circular arrangement of the cycle with clear directionality helps readers understand the pathway flow.\n\n2. Compartmentalization: The diagram correctly represents the subcellular localization of enzymes across the cytosol, mitochondrion, and mitochondrial inner membrane as specified in the GO-CAM data.\n\n3. Enzyme classification: The color-coding of enzymes by functional class (oxidoreductases, transferases, hydratases, ligases, and carboxylases) adds an informative layer that helps with understanding enzyme functions.\n\n4. Cofactors and additional reactions: The inclusion of NAD+/NADH conversions, CO2 release, and CoA/ATP involvement accurately represents the chemistry of the cycle.\n\n5. Gene products: All enzymes are labeled with their yeast gene names as provided in the GO-CAM data, maintaining fidelity to the source information.\n\nThe addition of a contextual note about yeast-specific aspects of the TCA cycle enhances the biological relevance of the illustration for readers.","necessary_changes":null,"optional_changes":null}