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Transcription coregulator activity

The activity unit for a transcription coregulator is:

  • MF: a child of transcription coregulator activity (GO:0003712):
  • transcription coactivator activity (GO:0003713)
  • transcription corepressor activity (GO:0003714)
  • Context:
  • has input:the transcription factor regulated, when known.
  • BP in which this transcriptional event is involved
  • CC: this activity occurs in the nucleus.
  • The causal relation between the transcription coregulator activity and the transcription factor activity unit is ‘directly positively regulates’ or 'directly negatively regulates.

  • If the causal relation between the coregulator and the target gene regulated needs to be captured, the causal relation is: ‘indirectly positively regulates’ or 'indirectly negatively regulates’, since there are many steps between the regulation of transcription and the activity of the target protein.

Example: GO:0003714 transcription corepressor activity

Example: GO:0003713 transcription coactivator activity

Example: GO:0003712 transcription coregulator activity (BMAL1 binds specifically DNA)

Example: Coregulator of an unknown transcription factor

Review information

To be reviewed date:

Created by: Cristina Casals